Drug or drug class	NNT	Outcome prevented
ACE inhibitors14	6	One death over one year in patients with NYHA class III and IV failure
	100	One death over one year in patients with NYHA class I or II failure
Beta blockers15	23	One death over one year
	13	One hospitalization over one year
Spironolactone2	9	One death over two years in patients with NYHA class IV failure
Hydralazine and isosorbide dinitrate13	14	One death over one year
Digoxin16	9	Emergency department visits or hospitalizations