Study	Number of patients	Treatment regimen	Number of deaths (%)	Number of cases of recurrent PE (%)
UPET (1970)4	78	Heparin	7 (8.9)	15 (19)
	82	Urokinase (12 hours)	6 (7.3)	12 (15)
PIOPED (1990)18	4	Heparin	0	NA
	9	rtPA	1 (11.1)
Levine, et al. (1990)6	25	Heparin	0	0
	33	rtPA	1 (3)	0
PAIMS 2 (1992)7	16	Heparin	1 (6.3)	3 (18.8)
	20	rtPA	2 (10)	1 (5)
Goldhaber (1993)17	55	Heparin	2 (3.6)	5 (9.1)
	46	rtPA	0	0