History and physical examination (including pelvic examination)

Assessment of compliance with hormonal contraception

Review of menstrual calendar

Pregnancy test

Papanicolaou's test (to evaluate for cervical pathology)

Appropriate laboratory tests (e.g., hemoglobin level, thyroid-stimulating hormone level, prolactin level)

Tests for Chlamydia trachomatis and Neisseria gonorrhoeae, if indicated

Pelvic ultrasonography, if indicated

Endometrial biopsy, if indicated