Timing of cardioversionAnticoagulation
Early cardioversion* in patients with atrial fibrillation for less than 48 hoursHeparin during cardioversion period to achieve PTT of 1.5 to2.5 times the baseline value
Early cardioversion* in patients with atrial fibrillation for more than 48 hours or an unknown duration, but without documented atrial thrombiHeparin during cardioversion period to achieve PTT of 1.5 to 2.5 times the baseline value
Warfarin (Coumadin) for 4 weeks after cardioversion to achieve target INR of 2.5 (range: 2.0 to 3.0)
Elective cardioversion in patients with atrial fibrillation for more than 48 hours or an unknown durationWarfarin for 3 weeks before and 4 weeks after cardioversion to achieve target INR of 2.5 (range: 2.0 to 3.0)