Drug	Class	Usual starting dosage for panic disorder	Typical therapeutic daily dose range	Maximum recommended daily dose	Representative monthly cost*†
Citalopram (Celexa)‡	SSRI	10 mg once daily	20 to 40 mg	60 mg	$65 to $67
Fluvoxamine (Luvox)	SSRI	25 mg once daily	100 to 200 mg	300 mg	$100 to $200
Fluoxetine (Prozac)‡	SSRI	10 mg once daily	20 to 60 mg	80 mg	$85 to $240
Paroxetine (Paxil)‡§	SSRI	10 mg once daily	20 to 40 mg	60 mg	$76 to $83
Sertraline (Zoloft)‡§	SSRI	25 mg once daily	100 to 200 mg	200 mg	$75 to $150
Imipramine (Tofranil)	TCA	10 to 25 mg once daily	100 to 200 mg	300 mg	$6 to $22
Clomipramine (Anafranil)	TCA	25 mg once daily	100 to 250 mg	250 mg	$100 to $250 ($66 to $250)
Alprazolam (Xanax)§	Benzodiazepine	0.25 mg three times daily	2 to 9 mg	10 mg	$78 to $312 ($6 to $45)
Clonazepam (Klonopin)§	Benzodiazepine	0.25 to 0.5 mg once daily or twice daily	1 to 4 mg	20 mg	$28 to $80 ($23 to $64)
Venlafaxine (Effexor)	Serotonin-norepinephrine reuptake inhibitor	37.5 mg once daily	150 to 225 mg	225 mg	$86 to $150
Nefazodone (Serzone)	Serotonin agonist/ antagonist	100 mg twice daily	300 to 600 mg	600 mg	$79 to $150
Mirtazapine (Remeron)	Adrenergic and serotonergic antagonist	7.5 mg once daily	15 to 30 mg	45 mg	$77 to $78
Phenelzine (Nardil)	MAOI	15 mg twice daily	45 to 90 mg	90 mg	$150 to $300 ($46 to $92)