FindingsDisorder suspectedFurther diagnostic studies
Snoring, daytime somnolence, obesityObstructive sleep apneaSleep study
Hypernatremia, hypokalemiaAldosteronismRatio of plasma aldosterone to plasma renin activity, CT scan of adrenal glands
Renal insufficiency, atherosclerotic cardiovascular disease, edema, elevated blood urea nitrogen and creatinine levels, proteinuriaRenal parenchymal diseaseCreatinine clearance, renal ultrasonography
Systolic/diastolic abdominal bruitRenovascular diseaseMagnetic resonance angiography, captopril (Capoten)-augmented radioisotopic renography, renal arteriography
Use of sympathomimetics, perioperative setting, acute stress, tachycardiaExcess catecholaminesConfirm patient is normotensive in absence of high catecholamines.
Decreased or delayed femoral pulses, abnormal chest radiographCoarctation of aortaDoppler or CT imaging of aorta
Weight gain, fatigue, weakness, hirsutism, amenorrhea, moon facies, dorsal hump, purple striae, truncal obesity, hypokalemiaCushing's syndromeDexamethasone-suppression test
Use of drug in Table 2Drug side effectTrial off drug, if possible
High salt intake, excessive alcohol intake, obesityDiet side effectsTrial of dietary modification
Erythropoietin use in renal disease, polycythemia in COPDErythropoietin side effectTrial off drug, if possible
Paroxysmal hypertension, headaches, diaphoresis, palpitations, tachycardiaPheochromocytomaUrinary catecholamine metabolites (vanillylmandelic acid, metanephrines, normetanephrines)
Plasma free metanephrines
Fatigue, weight loss, hair loss, diastolic hypertension, muscle weaknessHypothyroidismTSH levels
Heat intolerance, weight loss, palpitations, systolic hypertension, exophthalmos tremor, tachycardiaHyperthyroidismTSH levels
Kidney stones, osteoporosis, depression, lethargy, muscle weaknessHyperparathyroidismSerum calcium, parathyroid hormone levels
Headaches, fatigue, visual problems, enlargement of hands, feet, tongueAcromegalyGrowth hormone level