Antimicrobial agent	Dosage	Duration of therapy	Rating of evidence†
Clindamycin	Children: 20 to 30 mg per kg per day orally in three equally divided doses	10 days	B-II
	Adults: 600 mg per day in two to four equally divided doses‡	10 days	B-III
Amoxicillin–clavulanic acid	Children: 40 mg per kg per day orally in three equally divided doses§‖	10 days	B-II
	Adults: 500 mg twice daily‡‖	10 days	B-III
Penicillin G benzathine	For intramuscular dosages, see Table 1.∥	1 dose	B-II
Penicillin G benzathine with rifampin	Rifampin: 20 mg per kg per day orally in two equally divided doses	4 days