CauseFeatures
Allergic contact dermatitisSharply demarcated erythematous lesion with overlying vesicles
Reaction within two to seven days of exposure (see Table 2)
Atopic dermatitis“Itch that rashes (when scratched)” in patients with atopic conditions (e.g., allergic rhinitis, asthma)
Involvement of flexor wrists and ankles, as well as antecubital and popliteal fossae
Bullous pemphigoidInitially pruritic urticarial lesions, often in intertriginous areas
Formation of tense blisters after urticaria
Cutaneous T-cell lymphoma (mycosis fungoides)Oval eczematous patch on skin with no sun exposure (e.g., buttocks)
Possible presentation as new eczematous dermatitis in older adults
Possible presentation as erythroderma (exfoliative dermatitis)
Dermatitis herpetiformisRare vesicular dermatitis affecting lumbosacral spine, elbows, or knees
FolliculitisPruritus out of proportion to appearance of dermatitis
Papules and pustules at follicular sites on chest, back, or thigh
Lichen planusLesions often located on the flexor wrists “6Ps”: pruritus, polygonal, planar, purple papules, and plaques
Pediculosis (lice infestation)Occiput of school-aged children; genitalia in adults (sexually transmitted disease)
PsoriasisPlaques on extensor extremities, low back, palms, soles, and scalp
ScabiesBurrows in hand web spaces, axillae, and genitalia
Hyperkeratotic plaques, pruritic papules, or scales
Face and scalp affected in children but not in adults
Sunburn teroidalPossible photosensitizing cause (e.g., nonsteroidal anti-inflammatory drugs, cosmetics)
Xerotic eczemaIntense itching in elderly patients (often during winter months in northern climates)
Involvement of back, flank, abdomen, waist, and distal extremities