| Symptomatic primary hyperparathyroidism (nephrolithiasis, nephrocalcinosis, osteitis fibrosa cystica) |
| Asymptomatic primary hyperparathyroidism |
| Serum calcium level > 1.0 mg per dL (0.25 mmol per L) above the upper limits of normal |
| Urinary calcium excretion > 400 mg per 24 hours (10 mmol per day) |
| Creatinine clearance reduced by more than 30 percent compared with age-matched persons |
| Bone density (lumbar spine, hip, or forearm) that is > 2.5 standard deviations below peak bone mass (T score -2.5) |
| Patient age < 50 years, with asymptomatic primary hyperparathyroidism |
| Medical surveillance not desirable or possible |
| Surgery requested by patient |