Symptomatic primary hyperparathyroidism (nephrolithiasis, nephrocalcinosis, osteitis fibrosa cystica)
Asymptomatic primary hyperparathyroidism
Serum calcium level > 1.0 mg per dL (0.25 mmol per L) above the upper limits of normal
Urinary calcium excretion > 400 mg per 24 hours (10 mmol per day)
Creatinine clearance reduced by more than 30 percent compared with age-matched persons
Bone density (lumbar spine, hip, or forearm) that is > 2.5 standard deviations below peak bone mass (T score -2.5)
Patient age < 50 years, with asymptomatic primary hyperparathyroidism
Medical surveillance not desirable or possible
Surgery requested by patient