Hospitalize the patient if two or more of the following are present:
Respiratory rate >30 breaths per minute or 10 breaths above baseline
Oxygen saturation < 90 percent on room air
Systolic blood pressure < 90 mm Hg or 20 mm Hg less than baseline
Oxygen requirement of 3 L per minute more than baseline
Uncontrolled chronic obstructive pulmonary disease, congestive heart failure, or diabetes
If previously conscious, cannot be awakened
New or increased agitation
With the presence of any one of the above, hospitalization also is indicated if proper physical and human resources are not available (e.g., nursing staff, physician, oxygen, suction equipment, laboratory access, intravenous fluids).