Acute inflammatory demyelinating polyradiculoneuropathy (AIDP)

Autoimmune disorder, antibody mediated

Is triggered by antecedent viral or bacterial infection

Electrophysiologic findings demonstrate demyelination.

Inflammatory demyelination may be accompanied by axonal nerve loss.

Remyelination occurs after the immune reaction stops.

Acute motor axonal neuropathy (AMAN)

Pure motor axonal form of neuropathy

Sixty-seven percent of patients are seropositive for campylobacteriosis.

Electrophysiologic studies are normal in sensory nerves, reduced or absent in motor nerves.

Recovery is typically more rapid.

High proportion of pediatric patients

Acute motor sensory axonal neuropathy (AMSAN)

Wallerian-like degeneration of myelinated motor and sensory fibers

Minimal inflammation and demyelination

Similar to AMAN except AMSAN affects sensory nerves and roots

Typically affects adults

Miller Fisher syndrome

Rare disorder

Rapidly evolving ataxia, areflexia, mild limb weakness, and ophthalmoplegia

Sensory loss unusual, but proprioception may be impaired.

Demyelination and inflammation of cranial nerve III and VI, spinal ganglia, and peripheral nerves

Reduced or absent sensory nerve action potentials, tibial H reflex is usually absent.

Resolution occurs in one to three months.

Acute panautonomic neuropathy

Rarest of all the variants

Sympathetic, parasympathetic nervous systems are involved.

Cardiovascular involvement is common (postural hypotension, tachycardia, hypertension, dysrhythmias).

Blurry vision, dry eyes, and anhydrosis

Recovery is gradual and often incomplete.

Often combined with sensory features