Mechanism	Drug absorption (hapten)	Immune complex	Autoantibody
DAT Site of hemolysis Medications	Positive anti-IgG Extravascular Penicillin Ampicillin Methicillin Carbenicillin Cephalothin (Keflin)* Cephaloridine (Loridine)*	Positive anti-C3 Intravascular Quinidine Phenacetin Hydrochlorothiazide Rifampin (Rifadin) Sulfonamides Isoniazid Quinine Insulin Tetracycline Melphalan (Alkeran) Acetaminophen Hydralazine (Apresoline) Probenecid Chlorpromazine (Thorazine) Streptomycin Fluorouracil (Adrucil) Sulindac (Clinoril)	Positive anti-IgG Extravascular Alpha-methyldopa Mefenamic acid (Ponstel) l-dopa Procainamide Ibuprofen Diclofenac (Voltaren) Interferon alfa