Beta-blocker dosage		Carvedilol dosage
No overlap method
	Not currently receiving a beta blocker	Start carvedilol in a dosage of 3.125 mg twice daily; titrate dosage every one to two weeks to the maximum tolerated dosage or 25 mg twice daily.
	Metoprolol (Toprol XL), 50 mg per day, or atenolol (Tenormin), 50 mg per day	Start carvedilol in a dosage of 6.25 mg twice daily; titrate dosage every one to two weeks.
Overlap method
	Atenolol, 200 mg per day	Add carvedilol in a dosage of 3.125 mg twice daily for two weeks, then reduce dosage of atenolol to 150 mg daily for two weeks, then double the carvedilol dosage every two weeks while reducing the daily dosage of atenolol by 50 mg.
		When dosage of atenolol reaches 50 mg, decrease dosage to 25 mg daily for two weeks and discontinue.
	Atenolol, 50 to 150 mg per day	Add carvedilol in a dosage of 3.125 mg twice daily for two weeks, then double the carvedilol dosage every two weeks while reducing the atenolol dosage by 50 mg.
		When atenolol reaches 50 mg, decrease to 25 mg daily for two weeks and discontinue.
	Metoprolol, 100 to 200 mg per day	Add carvedilol in a dosage of 3.125 mg twice daily for two weeks, then double the carvedilol dosage every two weeks while reducing the daily metoprolol dosage by 50 mg.
		Discontinue metoprolol after two weeks of 50 mg per day.