Hazard ratio (CI)
Dose at day 45 (no. of patients)	Death	Death/heart failure hospitalization	Death/all hospitalization
None (5,746)	1.12 (1.02 to 1.22)	1.08 (1.00 to 1.16)	1.04 (0.98 to 1.10)
Low (3,935)*	1.00	1.00	1.00
Medium (4,316)	0.94 (0.86 to 1.03)	0.95 (0.88 to 1.02)	0.95 (0.89 to 1.00)
High (2,542)	0.76 (0.68 to 0.85)	0.87 (0.80 to 0.95)	0.87 (0.81 to 0.93)