Idiopathic (approximately 50 percent)
GI (most common, up to 50 percent of diagnosed cases)
Gastroesophageal reflux
Gastric volvulus
Intussusception
Swallowing abnormalities
Other GI abnormalities
Neurologic (approximately 30 percent)
Seizure disorder
Febrile seizure
CNS bleeding
Neurologic conditions affecting respiration (Budd-Chiari syndrome, hindbrain malformation, brainstem malformation)
Vasovagal reflexes
Hydrocephalus
CNS infection
Ventriculoperitoneal shunt malfunction
Malignancy
Respiratory (approximately 20 percent)
Respiratory compromise from infection, respiratory syncytial virus, pertussis, mycoplasma, croup, other pneumonias
Obstructive sleep apnea
Breath-holding spells
Conditions affecting respiratory control (prematurity, central hypoventilation)
Respiratory
Vocal cord abnormalities, adenoid vegetations
Laryngotracheomalacia
Airway obstruction resulting from congenital abnormalities
Foreign-body aspiration
Cardiac (up to 5 percent)
Arrhythmia
Long QT syndrome
Wolff-Parkinson-White syndrome
Congenital heart disease
Myocarditis
Cardiomyopathy
Metabolic abnormalities (less than 5 percent)
Inborn errors of metabolism
Endocrine, electrolyte disorders
Other infections
Urinary tract infection
Sepsis
Child abuse (less than 5 percent)
Munchausen syndrome by proxy (suffocation, intentional salt poisoning, medication overdose, physical abuse, head injury)
Smothering (unintentional or intentional)
Other
Food allergy (uncommon)
Anaphylaxis
Medication (prescription, over the counter, herbal remedies)