AgentDosage*Cost per course† (generic)Common adverse reactions‡
CephalosporinsMild diarrhea, rash
Cefotaxime (Claforan)1 g IV every six to eight hours$355 (330)
Cefpodoxime (Vantin)200 mg orally twice per day124 (110)
Cefprozil (Cefzil)500 mg orally twice per day192
Ceftriaxone (Rocephin)1 g IV every 24 hours392
Cefuroxime (Ceftin)500 mg orally twice per day219 oral
0.75 to 1.5 g IV every eight hours250 to 358 IV
ClindamycinsMild diarrhea,abdominal pain, pseudomembranous colitis, rash
Clindamycin (Cleocin)300 mg orally every six hours238 (148 to 168) oral
600 mg IV every eight hours250 IV
FluoroquinolonesMild diarrhea, nausea, vomiting, constipation, dizziness, headache
Gatifloxacin (Tequin)400 mg orally or IV once per day98 oral, 382 IV
Levofloxacin (Levaquin)500 mg orally or IV once per day56 oral, 438 IV
Moxifloxacin (Avelox)400 mg orally once per day107
MacrolidesMild diarrhea, nausea,vomiting,abdominal pain,rash
Azithromycin (Zithromax)500 mg orally for one dose, then 250 mg once per day for four doses49 to 60 oral
500 mg IV every 24 hours295 IV
Clarithromycin (Biaxin)500 mg orally twice per day96
Erythromycin500 mg orally every six hours17 (8 to 10) oral
500 to 1,000 mg IV every six hours(167) IV
PenicillinsMild diarrhea, nausea,vomiting,rash
Amoxicillin500 mg orally every eight hours4 (4 to 8)
875 mg orally every 12 hours20 (18 to 19)
Amoxicillin/clavulanate(Augmentin)875 mg/125mg orally every 12 hours166 (110 to 115)
Penicillin G1 to 3 mU IV every four hours(273)
Penicillin V500 mg orally four times per day15 (9 to 15)
TetracyclinesMild diarrhea, nausea, vomiting, phototoxicity
Doxycycline (Vibramycin)100 mg orally twice per day102 (16 to 21)