Parenteral regimen*
Cefotetan (Cefotan) 2 g IV every 12 hoursor cefoxitin (Mefoxin) 2 g IV every six hours†; plus doxycycline (Vibramycin) 100 mg orally or IV every 12 hours‡
Alternatives:
Clindamycin (Cleocin) 900 mg IV every eight hours§; plus gentamicin loading dose IV or IM (2 mg per kg) followed by a maintenance dose (1.5 mg per kg) every eight hours (single daily dosing may be substituted)
Ofloxacin (Floxin) 400 mg IV every 12 hoursor levofloxacin (Levaquin) 500 mg IV once daily; with or without metronidazole (Flagyl) 500 mg IV every eight hours
Ampicillin/sulbactam (Unasyn) 3 g IV every six hours; plus doxycycline 100 mg orally or IV every 12 hours
Oral regimen
Ofloxacin 400 mg orally twice daily for 14 days or levofloxacin 500 mg orally once daily for 14 days∥; with or without metronidazole 500 mg orally twice daily for 14 days
Alternative:
Ceftriaxone (Rocephin) 250 mg IM in a single dose or cefoxitin 2 g IM in a single dose with concurrent probenecid (Benemid) 1 g orally in single dose or other parenteral third-generation cephalosporin; plus doxycycline 100 mg orally twice daily for 14 days with or without metronidazole 500 mg orally twice daily for 14 days