Clinical recommendation	Evidence rating	References
Antidepressants (in particular, escitalopram [Lexapro], paroxetine [Paxil], sertraline [Zoloft] and venlafaxine [Effexor]) are effective treatments for serious worry-prone disorders (e.g., GAD, panic disorder, SAD, OCD, PTSD), even in the absence of major depression.	A	9,29–33
Psychological treatments, especially cognitive behavioral therapy tailored to the specific diagnosis, are effective for worry-prone disorders (e.g., GAD, panic disorder, SAD, OCD, PTSD, major depressive disorder/dysthymia, hypochondriasis).	A	10,13,24–28
Selective serotonin reuptake inhibitors can be considered for treatment of hypochondriasis, although evidence from controlled trials is lacking.	C	17,18