BMI of 40 kg per m2 or higher, or BMI of 35 kg per m2 or higher with serious obesity-related comorbidities (e.g., diabetes, obstructive sleep apnea, coronary artery disease, debilitating arthritis)

Previous failed weight loss attempts involving an integrated nonsurgical weight loss program including dietary modification, behavioral support, and appropriate exercise

Possession of appropriate motivation and psychological stability to understand risks and benefits of the procedure as well as the commitment to lifelong postoperative lifestyle changes and medical surveillance