Oral
Ofloxacin (Floxin) 400 mg orally twice daily for 14 days or levofloxacin (Levaquin) 500 mg orally once daily for 14 days;with or without metronidazole (Flagyl) 500 mg orally twice daily for 14 days
Alternative:
Ceftriaxone (Rocephin) 250 mg IM in a single dose or cefoxitin (Mefoxin) 2 g IM in a single dose with concurrent probenecid (Benemid) 1 g orally in single dose or other parenteral third-generation cephalosporin;plus doxycycline (Vibramycin) 100 mg orally twice daily for 14 dayswith or without metronidazole 500 mg orally twice daily for 14 days
Parenteral
Cefotetan (Cefotan) 2 g IV every 12 hours or cefoxitin 2 g IV every six hours;plus doxycycline 100 mg orally or IV every 12 hours
Alternatives:
Clindamycin (Cleocin) 900 mg IV every eight hours;plus gentamicin loading dose IV or IM (2 mg per kg) followed by a maintenance dose (1.5 mg per kg) every eight hours (single daily dosing may be substituted)
Ofloxacin 400 mg IV every 12 hoursor levofloxacin 500 mg IV once daily;with or without metronidazole 500 mg IV every eight hours
Ampicillin/sulbactam (Unasyn) 3 g IV every six hours;plus doxycycline 100 mg orally or IV every 12 hours