StageDuration(weeks)SymptomsComment
CatarrhalOne to twoLacrimation, low-grade fever, malaise, mild conjunctival inflammation, rhinorrhea, late-phase nonproductive cough
  • Insidious onset

  • Gradually worsening symptoms

ParoxysmalOne to sixParoxysms (bursts of coughing during a single exhalation) followed by an inspiratory “whooping” sound, post-tussive cyanosis, and emesis
  • Peaks after two weeks

  • Weight loss, leukocytosis, and lymphocytosis are common

In infants younger than six months (especially those younger than four weeks): apnea, bradycardia, prolonged cough, poor feeding, no paroxysms
ConvalescentTwo to 12Paroxysms gradually improve but recur with respiratory infections
  • White blood cell count normalizes