Clinical recommendation	Evidence rating	References
The preferred method for diagnosing endometriosis is direct visualization of lesions with histologic confirmation.	C	15
Danazol (Danocrine) may be used for pain relief in patients with endometriosis.	A	22
OCPs, progesterone-only OCPs, and medroxyprogesterone acetate (Provera) should be used as first-line therapies for treating pain associated with endometriosis.	A	24–26
Because gonadotropin-releasing hormone analogues provide equivalent pain relief as OCPs and progestogens with more side effects, they should be used only as second- or third-line agents.	A	27
Surgical ablation of endometrial deposits with or without laparoscopic uterine nerve ablation can be performed for pain relief.	B	30,31
Laparoscopic surgery can be performed in women with subfertility and endometriosis.	B	32
Presacral neurectomy can be performed in women with midline abdominal pain from endometriosis.	B	31
Laparoscopic cystectomy is preferred over drainage for pain relief in women with endometriosis.	B	33