Abdominal wall vascular collaterals (caput medusa)
Ascites
Asterixis
Clubbing and hypertrophic osteoarthropathy
Constitutional symptoms, including anorexia, fatigue, weakness, and weight loss
Cruveilhier-Baumgarten murmur—a venous hum in patients with portal hypertension
Dupuytren’s contracture
Fetor hepaticus—a sweet, pungent breath odor
Gynecomastia
Hepatomegaly
Jaundice
Kayser-Fleischer ring—brown-green ring of copper deposit around the cornea, pathognomonic for Wilson’s disease
Nail changes:
Muehrcke’s nails—paired horizontal white bands separated by normal color
Terry’s nails—proximal two thirds of nail plate appears white, whereas the distal one third is red
Palmar erythema
Scleral icterus
Vascular spiders (spider telangiectasias, spider angiomata)
Splenomegaly
Testicular atrophy