Assess and stratify women into high, intermediate, lower, or optimal risk categories.

Lifestyle approaches (i.e., smoking cessation, regular exercise, weight management, and heart-healthy diet) to prevent CVD are AHA/ACC class I (SORT A*) recommendations for all women and a top priority in clinical practice.

Other CVD risk-reducing interventions should be prioritized on the basis of strength of recommendation and level of evidence, with the exception of lifestyle, which is a top priority for all women.

Highest priority is intervention in women at high risk.

Avoid interventions designated as AHA/ACC class III (e.g., hormone therapy, antioxidants; see Table 7).