Clinical recommendationEvidence ratingReferences
Localized granuloma annulare is self-limited and asymptomatic and usually does not require treatment.C1
Options for treatment of localized granuloma annulare include liquid nitrogen, injected steroids, and topical steroids.C18
Treatment for disseminated granuloma annulare should be undertaken in consultation with a dermatologist; options include dapsone, retinoids, antimalarial drugs, tacrolimus (Protopic), and pimecrolimus (Elidel).C1927,35,36