| | Clinically preventable burden† | Cost-effectiveness‡ | Total |
| Aspirin chemo-prophylaxis | To prevent cardiovascular events, discuss daily aspirin use with men older than 40 years, women older than 50 years, and others at increased risk of heart disease. | 5 | 5 | 10 |
| Childhood immunizationseries | Immunize children with diphtheria, tetanus, pertussis; measles, mumps, rubella; inactivated polio virus;Haemophilus influenzae type b; hepatitis B; varicella, pneumococcal conjugate; and influenza vaccines. | 5 | 5 | 10 |
| Tobacco-use screening and brief intervention | Screen adults for tobacco use, provide brief counseling, and offer pharmacotherapy. | 5 | 5 | 10 |
| Colorectal cancer screening | Routinely screen adults 50 years and older with fecal occult blood testing, sigmoidoscopy, or colonoscopy. | 4 | 4 | 8 |
| Hypertension screening | Routinely measure blood pressure in adults, and treat with antihypertensive medication to prevent cardiovascular disease. | 5 | 3 | 8 |
| Influenza immunization (adults) | Immunize adults 50 years and older against influenza annually. | 4 | 4 | 8 |
| Pneumococcal immunization (adults) | Immunize adults 65 years and older against pneumococcal disease (one dose is adequate for most persons in this population). | 3§ | 5 | 8 |
| Problem drinking screening and brief counseling | Routinely screen adults for alcohol use that places them at increased risk, and provide brief counseling with follow-up. | 4 | 4§ | 8 |
| Vision screening (adults) | Routinely screen adults 65 years and older for visual acuity with the Snellen chart. | 3 | 5 | 8 |
| Cervical cancer screening | Within three years of onset of sexual activity or at 21 years of age, routinely screen with cervical cytology women who are sexually active and have a cervix. | 4 | 3 | 7 |
| Cholesterol screening | Routinely screen men 35 years and older and women 45 years and older for lipid disorders, and treat with lipid-lowering drugs to prevent cardiovascular disease. | 5§ | 2§ | 7 |
| Breast cancer screening | Routinely screen women 50 years and older with mammography alone or with clinical breast examination, and discuss screening with women 40 to 49 years of age to determine the age at which screening should be initiated. | 4 | 2 | 6 |
| Chlamydia screening | Routinely screen sexually active women younger than 25 years for chlamydia. | 2 | 4 | 6 |
| Calcium chemoprophylaxis | Counsel adolescent and adult women to use calcium supplements to prevent fractures. | 3§ | 3§ | 6 |
| Vision screening (children) | Routinely screen children younger than five years for amblyopia, strabismus, and visual acuity. | 2 | 4§ | 6 |
| Folic acid chemoprophylaxis | Routinely counsel women of childbearing age on the use of folic acid supplements to prevent birth defects. | 2 | 3 | 5 |
| Obesity screening | Routinely screen adults for obesity, and offer patients who are obese high-intensity counseling about diet, exercise, or both combined with behavioral interventions for at least one year. | 3 | 2 | 5 |
| Depression screening | Screen adults for depression in clinical practices with systems in place to ensure accurate diagnosis, treatment, and follow-up. | 3 | 1 | 4 |
| Hearing screening | Screen adults 65 years and older for hearing impairment, and make referrals to subspecialists. | 2 | 2 | 4 |
| Injury prevention counseling | Assess the safety practices of parents with children younger than five years, and provide them with safety counseling (e.g., child safety seats, window and stair guards, pool fence, poison control, hot water temperature, bicycle helmets). | 1 | 3§ | 4 |
| Osteoporosis screening | Routinely screen all women 65 years and older and women 60 years and older who are at increased risk for osteoporosis, and discuss the benefits and harms of treatment options. | 2 | 2 | 4 |
| Cholesterol screening (high risk) | Routinely screen men 20 to 35 years of age and women 20 to 45 years of age for lipid disorders if they have other risk factors for coronary heart disease, and treat with lipid-lowering drugs to prevent cardiovascular disease. | 1 | 1§ | 2 |
| Diabetes screening | Screen adults with high cholesterol levels or hypertension for diabetes, and treat with a goal of lowering blood pressure and cholesterol levels to below conventional target values. | 1 | 1 | 2 |
| Diet counseling | Offer intensive behavioral dietary counseling to adult patients with hyperlipidemia and other known risk factors for cardiovascular and diet-related chronic disease. | 1 | 1 | 2 |
| Tetanus-diphtheria booster | Immunize adults every 10 years. | 1 | 1 | 2 |