Clinical recommendation	Evidence rating	References
Nonpharmacologic therapy is recommended for all patients with overactive bladder.	A	17–19
All available anticholinergic agents effectively decrease the frequency of urgency and incontinence episodes; one should be offered to patients who remain symptomatic despite nonpharmacologic therapy.	A	26,31
Anticholinergics should be selected on the basis of cost and tolerability.	C	19,22,26,31
Extended-release formulations of oxybutynin (Ditropan) and tolterodine (Detrol) are better tolerated than immediate-release versions.	A	23–31
The lowest effective dose of anticholinergics should be prescribed to avoid dose-dependent adverse effects.	C	26,31