| High-potency, broad-spectrum (ultraviolet A and B) sunscreens may prevent melasma. | C | 1, 2 |
| Severe epidermal melasma may be treated postpartum with combinations of topical tretinoin (Retin-A), hydroquinone (Eldoquin Forte), and corticosteroids. | B | 9, 10 |
| Ursodeoxycholic acid (ursodiol [Actigall]) effectively reduces pruritus and serum bile acid levels in patients with severe intrahepatic cholestasis of pregnancy. | B | 18, 27 |
| Patients with intrahepatic cholestasis of pregnancy, impetigo herpetiformis, and pemphigoid gestationis should receive antepartum surveillance. | C | 18, 22 |