| Drug* | Safety | Tolerability | Effectiveness | Price | Simplicity |
|---|---|---|---|---|---|
| Hydrochlorothiazide (Esidrix) | F | F | F | SF | SF (once daily) |
| Lisinopril (Zestril) | V† | F | SF | V | SF (once daily) |
| Metoprolol tartrate (Lopressor) | F | F | SF | F | F (twice daily) |
| Metoprolol succinate (Toprol XL) | F | F | SF | U | SF (once daily) |