Clinical recommendationEvidence ratingReferencesComment
A “test-and-treat” strategy is recommended in patients with symptoms of dyspepsia.A915, 27 Test-and-treat strategy reduces endoscopies and use of antisecretory medications.
Helicobacter pylori eradication therapy is recommended to prevent recurrence and rebleeding in patients with peptic ulcer.A24 It is unnecessary to continue antisecretory maintenance therapy in patients after H. pylori eradication.
Short-course drug therapy is an option for H. pylori eradication in adult patients.C38, 39 Eradication rates using short-course therapy are similar to those of traditional treatment with the potential for greater compliance.
The urea breath test is the most reliable noninvasive diagnostic test in children with suspected H. pylori infection.C20, 21 Urea breath test is more reliable in children older than six years; monoclonal antibody-based stool antigen is an alternative.