Treatment regimen	Duration (days)	Number of patients studied	Population studied	Eradication rate (%)	Cost (generic) per day*
Bismuth subsalicylate (Pepto-Bismol), 524 mg four times a day, plus amoxicillin, 2 g four times a day, plus metronidazole (Flagyl), 500 mg four times a day, plus lansoprazole (Prevacid), 60 mg once38	1	80	H. pylori–positive patients with dyspepsia	95	Bismuth subsalicylate: $1
					Amoxicillin: $9 (8 to 12)
					Metronidazole: $18 (2 to 7)
					Lansoprazole: $20
Clarithromycin (Biaxin), 500 mg twice daily, plus amoxicillin, 1 g twice daily, plus lansoprazole, 30 mg twice daily38	7	80	H. pylori–positive patients with dyspepsia	90	Clarithromycin: $10 (9)
					Amoxicillin: $2 (2 to 3)
Amoxicillin, 1 g twice daily, plus metronidazole, 400 mg twice daily, plus clarithromycin, 250 mg twice daily, plus lansoprazole, 30 mg twice daily39	5	83	H. pylori–positive patients with dyspepsia for three months or endoscopically confirmed ulcers	89	Amoxicillin: $2 (2 to 3)
					Metronidazole: $9 (1 to 4) for 500-mg strength
					Clarithromycin: $10 (9)
					Lansoprazole: $10
Amoxicillin, 1 g twice daily, plus metronidazole, 400 mg twice daily, plus clarithromycin, 250 mg twice daily, plus ranitidine (Zantac), 300 mg twice daily39	5	80	H. pylori–positive patients with dyspepsia for three months or endoscopically confirmed ulcers	89	Amoxicillin: $2 (2 to 3)
					Metronidazole: $9 (1 to 4) for 500-mg strength
					Clarithromycin: $10 (9)
					Ranitidine: $10 (6)
Lansoprazole, 30 mg twice daily for two days (pretreatment), plus amoxicillin, 1 g twice daily, plus metronidazole, 400 mg twice daily, plus clarithromycin, 250 mg twice daily, plus lansoprazole, 30 mg twice daily39	5	80	H. pylori–positive patients with dyspepsia for three months or endoscopically confirmed ulcers	81	Lansoprazole (pretreatment): $10
					Amoxicillin: $2 (2 to 3)
					Metronidazole: $9 (1 to 4) for 500-mg strength
					Clarithromycin: $10 (9)
					Lansoprazole: $10