Clinical recommendationEvidence ratingReferences
Antibiotics are not recommended for treatment of the common cold in children or adults.A14, 15
Dextromethorphan (Delsym) is a treatment option for adults with cough caused by the common cold.B5, 19
Topical (intranasal) or oral nasal decongestants, used for up to three days, is a treatment option for adolescents and adults.B7, 8, 30
Topical ipratropium (Atrovent) is a treatment option for nasal congestion in children older than six years and in adults, although it is expensive.B9
Codeine (Robitussin AC) and other narcotics, dextromethorphan (Delsym), antihistamines, and combination antihistamine/decongestants are not recommended to treat cough or other cold symptoms in children.B57, 10, 17
Older first-generation antihistamines and combination antihistamine/decongestants are treatment options for cough and cold symptoms in adults if the benefits outweigh the adverse effects.B6
Among available complementary treatments, vitamin C prophylaxis may decrease the severity and duration of cold symptoms; however, vitamin C, zinc, and Echinacea are not recommended for active treatment.B3134, 36