Essential features*
Pruritus
Eczema (acute, subacute, chronic)
	Typical morphology and age-specific patterns (i.e., facial, neck, and extensor involvement in children; current or previous flexural lesions in any age group; sparing of groin and axillary regions)
	Chronic or relapsing history
Important features†
Onset at early age
Atopy
	Personal or family history
	Immunoglobulin E reactivity
Xerosis
Associated features‡
Atypical vascular responses (e.g., facial pallor, white dermatographism, delayed blanch response)
Keratosis pilaris, hyperlinear palms, and ichthyoses
Ocular or periorbital changes
Other regional findings (e.g., perioral changes, periauricular lesions)
Perifollicular accentuation, lichenification, and prurigo lesions