Effectiveness	Irritable bowel syndrome symptoms: probably effective
	Non-ulcer dyspepsia: probably effective
	Reducing spasm during gastrointestinal procedures: probably effective
	Tension headache: probably effective
Adverse effects	Common: allergic reactions, heartburn, perianal burning, blurred vision, nausea, and vomiting
	Rare: interstitial nephritis, acute renal failure
Interactions	May inhibit the cytochrome P450 1A2 system
Contraindications	Hiatal hernia, severe gastroesophageal reflux, gallbladder disorders; use with caution in pregnant and lactating women
Dosage	Adults: 0.2 to 0.4 mL of oil three times daily in enteric-coated capsules
	Children older than eight years: 0.1 to 0.2 mL three times daily
Cost	$24 to $32 for one-month supply
Bottom line	Safe at proper dosages and moderately effective in patients with functional gastrointestinal conditions