Clinical recommendation	Evidence rating	References
Peppermint oil seems to be a safe alternative for reducing symptoms of irritable bowel syndrome, although the evidence supporting this use is unclear.	B	4,9
Peppermint oil given via enema can be used for reducing colonic spasm in patients undergoing barium enema.	B	10,11
In combination with caraway oil, peppermint oil can be used for reducing symptoms of non-ulcer dyspepsia.	B	12,13
Peppermint oil can be applied topically to relieve headache.	B	15,16