Medication class (number of trials)Study lengthNumber of subjectsRanges of A1C reductions (%)
Sulfonylurea (4)12 weeks to 10 years204 to 3,8670.9 to 2.5
Alpha glucosidase inhibitor (12)16 weeks to 2 years40 to 4950.4 to 1.3
Metformin (7)11 weeks to 10.7 years27 to 7530.8 to 3.0
Meglitinide (4)12 to 24 weeks93 to 7010.6 to 1.7
Thiazolidinedione (4)24 to 26 weeks402 to 9591.1 to 1.6