Drug	Usual dosage*	Dosage adjustment (percentage of usual dosage) based on GFR (mL per minute per 1.73 m2)
		> 50	10 to 50	< 10
ACE inhibitors†
Benazepril (Lotensin)	10 mg daily	100%	50 to 75%	25 to 50%
Captopril (Capoten)	25 mg every 8 hours	100%	75%	50%
Enalapril (Vasotec)	5 to 10 mg every 12 hours	100%	75 to 100%	50%
Fosinopril (Monopril)‡	10 mg daily	100%	100%	75 to 100%
Lisinopril (Zestril)	5 to 10 mg daily	100%	50 to 75%	25 to 50%
Quinapril (Accupril)	10 to 20 mg daily	100%	75 to 100%	75%
Ramipril (Altace)5	5 to 10 mg daily	100%	50 to 75%	25 to 50%
Beta blockers
Acebutolol (Sectral)	400 to 600 mg once or twice daily	100%	50%	30 to 50%
Atenolol (Tenormin)	5 to 100 mg daily	100%	50%	25%
Bisoprolol (Zebeta)§	10 mg daily	100%	75%	50%
Nadolol (Corgard)5	40 to 80 mg daily	100%	50%	25%
Diuretics
Amiloride (Midamor)	5 mg daily	100%	50%	Avoid
Bumetanide (Bumex)5	No adjustment needed	—	—	—
Furosemide (Lasix)5	No adjustment needed	—	—	—
Metolazone (Zaroxolyn)	No adjustment needed	—	—	—
Spironolactone (Aldactone)5	50 to 100 mg daily	Every 6 to 12 hours	Every 12 to 24 hours	Avoid
Thiazides|	25 to 50 mg daily	100%	100%	Avoid
Torsemide (Demadex)5	No adjustment needed	—	—	—
Triamterene (Dyrenium)	50 to 100 twice daily	100%	100%	Avoid