| Dosage* and years of use | Oral | Transdermal | ||||||
|---|---|---|---|---|---|---|---|---|
| N | Observed | Expected | SIR | N | Observed | Expected | SIR | |
| Low | ||||||||
| 0.5 to five | 3,067 | 28 | 37 | 0.75 | 1,844 | 24 | 26 | 0.94 |
| More than five | 2,133 | 21 | 18 | 1.15 | 739 | 10 | 6 | 1.60 |
| Medium | ||||||||
| 0.5 to five | 408 | 2 | 1 | 1.60 | 7,006 | 102 | 104 | 0.99 |
| More than five | 1,738 | 20 | 15 | 1.38 | 8,445 | 104 | 76 | 1.32 |
| High | ||||||||
| 0.5 to five | 6,837 | 88 | 90 | 0.98 | 6,583 | 98 | 89 | 1.10 |
| More than five | 9,532 | 130 | 87 | 1.49 | 1,677 | 20 | 14 | 1.44 |