Class of medication	Common uses	Common side effects
Anticholinergic* (scopolamine [Maldemar]	Possible adjunct for cytotoxic chemotherapy, prophylaxis and treatment of motion sickness	Drowsiness, dry mouth, vision disturbances
Antihistamines (cyclizine [Marezine], diphenhydramine [Benadryl], dimenhydrinate [Dramamine], meclizine [Antivert])	Migraine, motion sickness, vertigo	Drowsiness
Benzodiazepines (alprazolam [Xanax], diazepam [Valium], lorazepam [Ativan])	Adjunct for chemotherapy-related symptoms	Sedation
Butyrophenones (droperidol [Inapsine†], haloperidol [Haldol])	Anticipatory and acute chemotherapeutic nausea and vomiting, postoperative nausea and vomiting	Agitation, restlessness, sedation
Cannabinoids (dronabinol [Marinol])	Refractory chemotherapy-related nausea and vomiting	Ataxia, dizziness, euphoria, hypotension, sedation
Corticosteroids (dexamethasone)	Adjunct for chemotherapy-related symptoms	Increased energy, insomnia, mood changes
Phenothiazines (chlorpromazine [Thorazine†], prochlorperazine, promethazine [Phenergan])	Migraine, motion sickness, postchemotherapy nausea and vomiting, postoperative nausea and vomiting, severe episodes of nausea and vomiting, vertigo	Extrapyramidal symptoms (e.g., dystonia, tardive dyskinesia), orthostatic hypotension, sedation
Serotonin 5-hydroxytryptamine antagonists‡ (dolasetron [Anzemet], odansetron [Zofran], granisetron [Kytril], palonosetron [Aloxi])	Postchemotherapy nausea and vomiting, severe nausea and vomiting	Asthenia, constipation, dizziness, mild headache
Substituted benzamides* (metoclopramide [Reglan], trimethobenzamide [Tigan])	Diabetic gastroenteropathy, gastroparesis	Extrapyramidal side effects (e.g., akathisia, dyskinesia, dystonia, oculogyric crises, opisthotonos), fatigue, hyperprolactinemia