Clinical conditionHistoryPhysical examinationDiagnostic imaging
Patellofemoral pain syndrome
  • Anterior knee pain exacerbated by running, jumping, or cycling

  • Pain on climbing or descending stairs or hills

  • Pain with prolonged sitting with knees flexed (i.e., “theater sign”)

  • Patellofemoral malalignment

  • “J” sign (i.e., curvilinear lateral tracking of the patella with contraction of quadriceps)

  • Tenderness along patellofemoral facets and pain with patellar compression

  • Crepitus with active extension

  • Radiography (sunrise or merchant view) often normal but may show lateral tilt or subluxation of patella

  • Computed tomography and MRI usually not indicated but may reveal patellar malalignment or chondromalacia

Iliotibial band friction syndrome
  • Lateral knee pain exacerbated by running, cycling, or hiking

  • May be aggravated by prolonged hill running, running on a slanted road shoulder, or too much unidirectional running around a track

  • Tenderness along lateral femoral condyle or approximately 2 cm above lateral joint line

  • Tight iliotibial band with Ober's test (i.e., passive adduction of hip and leg, with patient lying on unaffected side and knee slightly flexed)

  • Imaging usually not indicated when diagnosis is strongly suspected on clinical examination

  • Radiography typically normal

  • MRI may show thickened iliotibial band and associated edema

Medial tibial stress syndrome (i.e., shin splints)
  • Activity-associated shin pain described as dull ache along mid- to distal tibia

  • Tenderness along posteromedial border of the mid- to distal tibia for several centimeters

  • Focal tenderness over anterior tibia suggests stress fracture

  • Radiography typically normal

  • MRI or bone scan may determine nature of injury if stress fracture is suspected or patient has poor response to rest and treatment

Achilles tendinopathy
  • Gradual onset of pain in Achilles tendon

  • More common in middle-aged athletes

  • Acute injury with sensation of being struck in back of heel suggests rupture

  • Tenderness along Achilles tendon 2 to 6 cm proximal to attachment, often with thickened, tender nodules

  • Crepitus suggests acute tenosynovitis

  • Perform Thompson's test if rupture is suspected (i.e., assess passive ankle plantarflexion with calf squeeze; no response indicates tear)

  • Radiography usually not indicated but may show thickening of Achilles tendon or calcification at the insertion

  • MRI helpful if rupture is suspected and clinical evaluation is equivocal, although careful examination is usually diagnostic

  • Ultrasonography may be useful

Plantar fasciitis
  • Pain in plantar heel or arch that is worse with first few steps in the morning

  • Pain may subside with warm-up and activity, only to become stiff and sore after activity

  • Tenderness at medial plantar calcaneal tuberosity and along medial arch

  • Pain with passive dorsiflexion of the toes

  • Pes planus or pes cavus

  • Radiography usually not necessary but may show calcaneal spurring or calcifications within the plantar soft tissue

  • Presence or absence of heel spur does not change management

Stress fracture
  • Progressive pain over a bony structure that is worse with weight-bearing activity

  • Pain at rest in some cases

  • Physicians should maintain high suspicion of stress fracture in long distance runners with musculoskeletal pain

  • Focal tenderness over bony structure

  • Overlying edema may be present

  • In femoral neck stress fracture, pain with passive hip range of motion

  • Radiography often negative early in course of injury (less than two to four weeks)

  • May show cortical thickening, periosteal reaction, or fracture line

  • MRI and bone scan are more sensitive and should be performed if high-risk stress fracture (e.g., femoral neck or navicular fracture) is suspected

  • Dual energy x-ray absorptiometry may be indicated if osteoporosis is suspected