| Arthritis | Fatigue; joint deformity; joint pain that is often symmetrical; swelling | Erosion; fragmentation; joint space narrowing; soft-tissue swelling |
| Avascular necrosis of the metatarsal head (Freiberg's disease) | Pain, tenderness, swelling, and limitation of motion in the affected metatarsophalangeal joint | Collapse, cystic changes, and flattening of the metatarsophalangeal joint; sclerosis |
| Morton's neuroma | Often asymptomatic; pain in the involved web space that often radiates to the toes | Mass in intermetatarsal space |
| Painful accessory bones | Accessory tarsal navicular bones occur at the medial and posterior margins of the tarsal navicular, and os trigonum occurs adjacent to the posterior margin of the talus; pain and tenderness in the affected area | Marrow edema; presence of ossicle |
| Plantar fasciitis | Plantar heel pain | Fascial tear; marrow edema; plantar calcaneal spur |
| Reflex sympathetic dystrophy | Diminished motor function; pain and tenderness; swelling; vasomotor instability | Diffuse osteopenia; increased tracer uptake |
| Stress fracture | Limitation of motion; pain and tenderness in affected area | Callus formation; fracture line; periosteal reaction |
| Tarsal coalition | Bilateral in 50 percent of patients; restricted subtalar motion; rigid, painful flatfoot; valgus deformity of the hindfoot | C sign; flattening and broadening of the lateral talar process; narrowing of the talocalcaneal joint; talar breaking |
| Tarsal tunnel syndrome | Diffuse burning pain and paresthesias along the plantar surface of the foot and toes | Mass in the tarsal tunnel; synovial hypertrophy in tarsal tunnel |