Supplement	Typical dosage	Comments	Monthly cost*
Glucosamine	1,500 mg once daily or 500 mg three times daily	Glucosamine sulfate preferred over glucosamine hydrochloride	$9 to 35 (combination drugs appear to be in the same price range)
Chondroitin	200 to 400 mg two or three times daily	Combination chondroitin/glucosamine no better than glucosamine sulfate alone	$10 to 25
S-adenosylmethionine	200 mg three times daily	Butanedisulfonate salt form preferred for best stability and bioavailability	$60 to 120
Methylsulfonylmethane	500 mg three times daily to 3 g two times daily	Not recommended because of insufficient evidence	$5 to 35
Harpagophytum procumbens (devil's claw)	2.4 to 2.6 g daily standardized extract	Not recommended because of insufficient long-term safety data	$15 to 40
Curcuma longa (turmeric)	No typical dosage for osteoarthritis	Not recommended because of insufficient evidence	$8 to 23 (for one tablet daily)
Zingiber officinale (ginger)	510 mg daily standardized extract	Not recommended because of insufficient evidence	$2 to 3