Antibiotic prophylaxis is no longer recommended for patients with any form of congenital heart disease except those listed in Table 1

Antibiotic prophylaxis is not recommended based solely on an increased lifetime risk of infective endocarditis

Antibiotic prophylaxis is recommended only for patients with conditions listed in Table 1 who are undergoing dental procedures that involve manipulation of gingival tissues or periapical region of teeth, or perforation of the oral mucosa

Antibiotic prophylaxis is recommended only for patients with conditions listed in Table 1 who are undergoing procedures on the respiratory tract or infected skin, skin structures, or musculoskeletal tissue

Antibiotic prophylaxis solely to prevent infective endocarditis is not recommended for patients undergoing gastrointestinal or genitourinary tract procedures

Prophylaxis for infective endocarditis is not recommended in patients undergoing ear or body piercing, tattooing, vaginal delivery, or hysterectomy

Recommendations for prophylaxis of infective endocarditis should be limited to patients with conditions listed in Table 1