DiagnosisFeatures that differentiate from trigeminal neuralgia
Cluster headacheLonger-lasting pain; orbital or supraorbital; may cause patient to wake from sleep; autonomic symptoms
Dental pain (e.g., caries, cracked tooth, pulpitis)Localized; related to biting or hot or cold foods; visible abnormalities on oral examination
Giant cell arteritisPersistent pain; temporal; often bilateral; jaw claudication
Glossopharyngeal neuralgiaPain in tongue, mouth, or throat; brought on by swallowing, talking, or chewing
Intracranial tumorsMay have other neurologic symptoms or signs
MigraineLonger-lasting pain; associated with photophobia and phonophobia; family history
Multiple sclerosisEye symptoms; other neurologic symptoms
Otitis mediaPain localized to ear; abnormalities on examination and tympanogram
Paroxysmal hemicraniaPain in forehead or eye; autonomic symptoms; responds to treatment with indomethacin (Indocin)
Postherpetic neuralgiaContinuous pain; tingling; history of zoster; often first division
SinusitisPersistent pain; associated nasal symptoms
SUNCTOcular or periocular; autonomic symptoms
Temporomandibularjoint syndromePersistent pain; localized tenderness; jaw abnormalities
Trigeminal neuropathyPersistent pain; associated sensory loss