Second-generation antipsychotic	Agents that lead to increased antipsychotic drug levels	Agents that lead to decreased antipsychotic drug levels
Aripiprazole (Abilify)	Clarithromycin (Biaxin)*	Barbiturates
	Erythromycin*	Carbamazepine (Tegretol)
	Grapefruit juice*	Phenytoin (Dilantin)
	Itraconazole (Sporanox)*
	Ketoconazole (Nizoral)*
	Quinidine*
Clozapine (Clozaril)	Caffeine	Barbiturates
	Cimetidine (Tagamet)	Carbamazepine
	Ciprofloxacin (Cipro)	Nicotine
	Citalopram (Celexa)	Phenytoin
	Erythromycin	Rifampin (Rifadin)
	Fluoxetine (Prozac)
	Fluvoxamine (Luvox)
	Grapefruit juice
	Paroxetine (Paxil)
	Sertraline (Zoloft)
Olanzapine (Zyprexa)	Ciprofloxacin	Carbamazepine
	Fluvoxamine	Nicotine
		Omeprazole (Prilosec)
		Phenytoin
		Rifampin
Quetiapine (Seroquel)	Clarithromycin	Barbiturates
	Erythromycin	Carbamazepine
	Fluconazole (Diflucan)	Phenytoin
	Grapefruit juice	Rifampin
	Itraconazole	Theophylline
	Ketoconazole
Risperidone (Risperdal)	Clozapine	Barbiturates
	Fluoxetine	Carbamazepine
	Paroxetine	Phenytoin
		Rifampin
Ziprasidone (Geodon)	Clarithromycin	Carbamazepine
	Erythromycin	Phenytoin
	Fluconazole
	Grapefruit juice
	Itraconazole
	Ketoconazole