Clinical recommendationEvidence ratingReferences
Skeletal muscle relaxants are not considered first-line therapy for musculoskeletal conditions.C12, 13, 15
Skeletal muscle relaxants may be used as adjunctive therapy for acute low back pain.B17, 18
Antispasmodic agents should be used short-term (two weeks) for acute low back pain.C17, 18
There is no clear evidence that one skeletal muscle relaxant is superior to another for musculoskeletal spasms.B17, 18
Choice of skeletal muscle relaxant should be based on individual drug characteristics and patient situation.C32