What are the effects of treatments for acute diarrhea in adults living in resource-rich countries?
Likely to be beneficial	Antimotility agents
	Antisecretory agents
Trade-off between benefits and harms	Antibiotics (empiric use for mild-to-moderate diarrhea)
Unknown effectiveness	Antibiotics plus antimotility agents
	Restricted diet
	Oral rehydration solutions
What are the effects of treatments for mild-to-moderate traveler's diarrhea in adults from resource-rich countries traveling to resource-poor countries?
Likely to be beneficial	Antibiotics (empiric use)
	Antimotility agents
	Bismuth subsalicylate (reduced duration of diarrhea compared with placebo, but less effective than loperamide)
Trade-off between benefits and harms	Antisecretory agents
Unknown effectiveness	Antibiotics plus antimotility agents
	Restricted diet
	Oral rehydration solutions
What are the effects of treatments for mild-to-moderate diarrhea in adults living in resource-poor countries?
Likely to be beneficial	Antimotility agents
	Antisecretory agents
Unknown effectiveness	Antibiotics (empiric use)
	Antibiotics plus antimotility agents
	Oral rehydration solutions
What are the effects of treatments for severe diarrhea in adults living in resource-poor countries?
Beneficial	Amino acid–based oral rehydration solutions
	Rice-based oral rehydration solution
	Standard oral rehydration solution*
Unknown effectiveness	Antibiotics (empiric use)
	Antibiotics plus antimotility agents
	Antimotility agents
	Antisecretory agents
	Bicarbonate oral rehydration solution
	Intravenous rehydration (compared with nasogastric tube rehydration or oral rehydration solution alone)
	Reduced osmolarity oral rehydration solution