Condition	Characteristics
Liver failure	Edema caused by portal congestion or hypoalbuminemia, depending on severity of hepatic damage
Lymphedema	Edema caused by damage to, or maldevelopment of, the peripheral lymphatic system
Myxedema	Soft-tissue edema in patients with severe and advanced hypothyroidism; typically associated with other hypothyroid manifestations, such as bradycardia, constipation, and weight gain
Nephrotic syndrome	Edema caused by hypoproteinemia or hypoalbuminemia secondary to kidney disease
Systolic heart failure	Decreased cardiac ejection fraction leads to pulmonary, hepatic, and peripheral venous congestion
Thrombosis (portal vein, extremity, inferior vena cava)	Edema caused by thrombotic obstruction of venous drainage
Venous insufficiency	Edema caused by failure of venous return secondary to deep venous damage and/or incompetence