Mole or melanomaClinical features
Age at onsetLocationNumberSizeColor distributionShapeBorder
Normal molesAfter six to 12 months of age, usually by 20 years of age
  • Any site, relative spanning of sun-protected sites

Few to 100sMost < 6 mm in diameter
  • Orderly, symmetric distribution

  • Usually no more than two shades of brown

Round, ovalSmooth, regular, well-demarcated
Atypical molesAfter six to 12 months of age, usually by 20 years of age
  • Any site, even sun-protected areas

  • Chest

  • Back most heavily involved

One to 100sNo lower size limit
  • Disorderly

  • More than two shades of brown

  • Dark pigmentation

Round, oval, asymmetricIrregular and/or poorly demarcated, fuzzy
Usually > 6 mm in diameter
MelanomaAdulthood
  • Men: most often trunk

  • Women: most often lower extremities, but can be any location where pigment cells are found

OneNo lower size limit to > 6 mm in diameter
  • Change in color

  • More than two shades of brown

  • Very dark pigmentation

AsymmetricIrregular
It can occur in children with giant congenital moles, atypical mole syndrome, or xeroderma pigmentosum