Clinical recommendation	Evidence rating	References
Compared with standard hospital mattresses, pressure-reducing devices decrease the incidence of pressure ulcers.	A	10, 14
There is no evidence to support the routine use of nutritional supplementation (vitamin C, zinc) and a high-protein diet to promote the healing of pressure ulcers.	C	19
Heel ulcers with stable, dry eschar do not need debridement if there is no edema, erythema, fluctuance, or drainage.	C	8, 16
Ulcer wounds should not be cleaned with skin cleansers or antiseptic agents (e.g., povidone-iodine [Betadine], hydrogen peroxide, acetic acid) because they destroy granulation tissue.	B	8, 27, 28